Complimentary 2-day shipping on all orders $75+!
Get 2-Day Today
 

Whether you’re shopping for Mom, a new grad, or yourself, get complimentary 2-day shipping on orders $75+!

Free two-day shipping on orders over $75+. Excludes orders of only gift cards. Free two-day shipping is valid on qualifying orders placed from 4/30/25 at 3 a.m. ET through 5/7/25 at 3 a.m. ET.

 
store locator image
Scroll to bottom
now $69.00
be a firm believer
Protini Cream container on top of a pink acrylic stand on a yellow and green background.
A birds eye view GIF of Protini Cream being pumped out on a blue background.
A smear of Protini Cream on top of hand.
Two 50ml Protini Creams and Protini Cream 15ml Littles.

Protini Polypeptide Cream 50 ML

A (refillable!) peptide-packed gel-cream moisturizer that immediately improves the appearance of skin's tone, texture, and firmness
Complimentary 2-day shipping on all orders $75+!
Size:
50 ML/1.69 FL OZ
50 ML/1.69 FL OZ Refill
15 ML/.5 FL OZ
100 ML/3.3 FL OZ
Size:
Select Size regimen-dropdown-icon
OUT OF STOCK - Standard (50 ML/1.69 FL OZ)
OUT OF STOCK - Refill (50 ML/1.69 FL OZ)
OUT OF STOCK - Little (15 ML/.5 fl OZ)
OUT OF STOCK - Big (100 ML/3.3 FL OZ)
purchase option
$69.00
$69.00 $62.10
Replenishment:
10% off + Free Shipping
  • 10% off + Free Shipping
Cancel or manage your subscription at any time. Pay when your order ships.

auto-replenishment

No one likes to come up empty. Select the auto-replenishment option on eligible items and choose your delivery frequency. You’ll get 10% off and free shipping on all auto-replenishment deliveries. Cannot be combined with other discount offers.

You'll receive a reminder email when your auto-replenishment order is ready to be shipped. You may cancel at any time up to 24 hours before your next shipment..

Orders to US territories and military addresses will ship via USPS Priority Mail for a cost of $10.95 and will take up to 21 business days to arrive.

Or four payment installments of $17.25 by Afterpay more info
Complimentary 2-day shipping on all orders $75+!
1

Protini Polypeptide Cream 50 ML

1

Strengthen

Moisturize

Delivers daily moisture in a lightweight gel-cream.

Visibly firms skin and supports healthy collagen production, restoring bounce.

Reduces the appearance of texture, fine lines, wrinkles, and sun damage.

Formulated at a skin-friendly pH of 4.0.

100% free of essential oils, silicones, fragrance/dyes, and solvent alcohols.

Dermatologist tested.

Apply morning and night to a clean, dry face. Use daily or in rotation with other Drunk Elephant moisturizers. May be mixed with any Drunk Elephant serum, treatment, or cream.

key ingredients

ingredientImage
Nine signal peptides (made up of amino acids, which form proteins in the skin) bind moisture to skin—plumping, firming, and restoring bounce.
ingredientImage
An excellent source of antioxidants and nutrients to replenish the skin. This ingredient is extremely moisturizing, soothing, and calming and supports healthy, youthful-looking skin.
ingredientImage
This B vitamin plays a central role in maintaining youthful, elastic skin. Skin is thirsty for folic acid, especially after exposure to sun.
Full list of ingredients:
Water/Aqua/Eau, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Extract, Nymphaea Alba Root Extract, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium PCA, PCA, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid/Glycolic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract
You'll Like These Odds
Clinically proven to reduce lines and wrinkles, improve skin’s firmness, texture, and tone, and increase skin’s hydration.
96%
showed improvement in skin’s tone, radiance, and luminosity*
93%
showed improvement in texture*
90%
showed improvement in skin’s hydration*
*In a clinical study with 31 people after 8 weeks
Background Image
After 4 weeks
Overlay Image
Before
squiggle border
Illustration of green dumbells on a purple floor, to symbolize Protini's firming and moisturizng benefits.

tip 1

Add a pump of Protini to your daily skincare smoothie for a boost of moisturizing, firming peptides.

Illustration of a womans face and neck.

tip 2

Apply to the neck and décolleté to get the same firming and moisturizing benefits below the jawline.

Illustration of protini Cream with a pump of cream on top along side a couple drop of D-Bronzi for a sunny glow effect.

tip 3

Create a sunny glow by mixing a couple drops of D-Bronzi with Protini.

We believe in second chances: I’m recyclable!

How-to-recycle
Wait! Don’t throw me away—I’m refillable! Or if you’re ready to recycle:

  • Step 1: Remove the cap and unscrew the pump from the white jar.
  • Step 2: Recycle the cap and white jar.
squiggle border
Own Your Power Smoothie

For firmer, hydrated, younger-looking skin

We think of our skincare routines as smoothies.

Because our products are biocompatible with skin and highly absorbable, simply mix a little of this and a drop of that in the palm of your hand and apply it all together.

learn more
Smoothie Top Off
Smoothie Ingredients

Make your smoothie

Smoothie 0
Protini Polypeptide Cream 50 ML
50 ML/1.69 FL OZ
Smoothie 1
Protini™ Powerpeptide Resurf Serum
30 ML/1 FL OZ
Smoothie 2
B-Hydra™ Intensive Hydration Serum
50 ML
  • face-Off
  • compare moisturizers
  • face-Off
  • compare moisturizers
  • face-Off
  • compare moisturizers
  • face-Off
  • compare moisturizers
  • face-Off
  • compare moisturizers
  • face-Off
  • compare moisturizers
Protini Polypeptide Cream 50 ML
KEY INGREDIENTS 9 signal peptides + pygmy waterlily
USE Anytime (day or night)
PERFECT WHEN YOU Want visibly firmer skin and collagen-production support
Lala Retro™ Whipped Cream
KEY INGREDIENTS Triple-ceramide blend + 5 African oils
USE Anytime (day or night)
PERFECT WHEN YOU Need moisture maintenance at any age
Bora Barrier™ Repair Cream
KEY INGREDIENTS 6-butterlipid complex + zinc and copper gluconates
USE Anytime (day or night)
PERFECT WHEN YOU Have chronically dry skin and need deeply reparative moisture
KEY INGREDIENTS
9 signal peptides + pygmy waterlily
USE
Anytime (day or night)
PERFECT WHEN YOU
Want visibly firmer skin and collagen-production support
KEY INGREDIENTS
Triple-ceramide blend + 5 African oils
USE
Anytime (day or night)
PERFECT WHEN YOU
Need moisture maintenance at any age
KEY INGREDIENTS
6-butterlipid complex + zinc and copper gluconates
USE
Anytime (day or night)
PERFECT WHEN YOU
Have chronically dry skin and need deeply reparative moisture

A NOTE FROM TIFFANY

Every day, I add protein powder to my smoothie for muscle support. I wanted a different kind of moisturizer that would do the same for my skin. Protini was born. Jam-packed with crazy levels of amino acids, signal peptides, and safe, synthetic growth factors (the good kind), this dreamy “get-sh*t-done” cream melts right into your skin to make it hydrated, bouncy, and balanced. I’m hoping you’ll fall #drunkinlove!

A signature of Tiffany

#barewithus
Shop All Skincare